I'm David Gerlach, a new Postdoc in the lab.

About me

I come from Germany. I studied and did my PhD in Tübingen. I worked on the cell wall of the Gram-positive bacterium Staphylococcus aureus, a very important human pathogen. Recently I joined the Brochado lab to learn about high-throughput and computational methods in antimicrobial research. 

My project

In my postdoctoral work I will develop high throughput quantitative approaches to investigate bactericidal antimicrobial combinations.

 

Publications

  • Gerlach, D. et al. Dynamics of cell wall-modifying phages in Staphyloccocus aureus (2020, in preparation)

  • Wolz, C., Gerlach, D. Ingmer, H. (2019). Temperate Phages of Staphylococcus aureus., Microbiol Spectrum 7( ):GPP3-0058-2018

  • Gerlach, D., Guo, Y., Stehle T., Peschel A. (2019). Reply to: Do not discard Staphylococcus aureus WTA as a vaccine antigen. Nature 572, pagesE3–E4

  • Mnich, ME., Dalen, R., Gerlach, D., et al. (2019). The C‐type lectin receptor MGL senses N‐acetylgalactosamine on the unique Staphylococcus aureus ST395 wall teichoic acid. Cellular Microbiology. 21:e13072.

  • Gerlach, D., Guo, Y., De Castro, C., Kim, S.H., Schlatterer, K., Xu, F.F., Pereira, C., Seeberger, P.H., Ali, S., Codee, J., et al. (2018). Methicillin-resistant Staphylococcus aureus alters cell wall glycosylation to evade immunity. Nature 563, 705-709

  • Li, X., Gerlach, D., Du, X., Larsen, J., Stegger, M., Kuhner, P., Peschel, A., Xia, G., and Winstel, V. (2015). An accessory wall teichoic acid glycosyltransferase protects Staphylococcus aureus from the lytic activity of Podoviridae. Sci Rep 5, 17219.

  • Koc, C., Gerlach, D., Beck, S., Peschel, A., Xia, G., and Stehle, T. (2015). Structural and enzymatic analysis of TarM glycosyltransferase from Staphylococcus aureus reveals an oligomeric protein specific for the glycosylation of wall teichoic acid. J Biol Chem 290, 9874-9885.

 

Visit

Würzburg University,

Biocenter, Chair of Microbiology

Am Hubland, 97074 Würzburg,

Germany

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Ana Rita Brochado

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